6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2314 | PF-431396 | FAK , PYK2 | |
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM). | |||
T2465 | PF-562271 | PF562271,PF 562271 | FAK , PYK2 , CDK |
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM). | |||
T6177 | PF-562271 besylate | PF-00562271 Besylate | FAK , PYK2 , CDK |
PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, exc... | |||
T1918 | NVP-TAE 226 | TAE226 | Apoptosis , FAK , c-Met/HGFR , PYK2 , IGF-1R |
NVP-TAE 226 (TAE226) is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK. | |||
T21768 | PF-562271 hydrochloride | PF-562271 HCl | FAK , PYK2 , CDK |
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other pr... | |||
T22397 | PF-4618433 | Others | |
PF-4618433 is a dual inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). |